Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (C-Term) antibody

Antigen: Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE)

Synonyms: IKKE, IKKI, IKK-i, KIAA0151, MGC125294, MGC125295, MGC125297, zgc:100844, IKBKE, MGC137373, MGC130907

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Catalog no.: ABIN360635

Additional Information

Characteristics: Synonyms: I kappa-B kinase epsilon, IKK-epsilon, IKK-E, IKKI, KIAA0151, Inducible I kappa-B kinase,IKK-I, Inhibitor of nuclear factor kappa-B kinase subunit epsilon

Alternative name: IKBKE / IKKE

Gene ID: 9641

Swiss-Prot: Q14164

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the C-terminal region of human IKKE.

Cross-Reactivity: Human

Isotype: Ig  (Matching secondary antibodies)

Description: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor,generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. Bythis basic mechanism, protein kinases mediate most of the signal transduction ineukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression,cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With morethan 500 gene products, the protein kinase family is one of the largest families of proteinsin eukaryotes. The family has been classified in 8 major groups based on sequencecomparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. TheAGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated proteinkinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent proteinkinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, thekinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases thatphosphorylate ribosomal protein S6 family (RSK).

Specificity: This antibody reacts to IKKE. Species: Human.

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: PBS with 0.09% (W/V) sodium azide

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Restrictions: For Research Use only