MAGI1 antibody (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1) (C-Term)

Details for Product anti-MAGI1 Antibody No. ABIN360704, Supplier: Log in to see
Antigen
  • CNKSR3
  • AIP-3
  • AIP3
  • BAIAP1
  • BAP-1
  • BAP1
  • MAGI-1
  • TNRC19
  • WWP3
  • Baiap1
  • Gukmi1
  • MAGI1c
  • Magi-1
  • mKIAA4129
  • membrane associated guanylate kinase, WW and PDZ domain containing 1
  • MAGI1
  • LOC100339815
  • Magi1
Epitope
C-Term
18
10
3
3
3
1
1
1
1
Reactivity
Human
46
8
6
1
1
Host
Rabbit
28
19
Clonality
Polyclonal
Conjugate
This MAGI1 antibody is un-conjugated
4
4
3
3
3
3
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
43
30
15
7
7
4
Options
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BAIAP1.
Isotype Ig
Specificity This antibody reacts to BAIAP1.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name MAGI1 / BAIAP1 (MAGI1 Antibody Abstract)
Background BAIAP1 is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. Characterized by two WW domains, a guanylate kinase domain, and five PDZ domains, this protein interacts with the cytoplasmic region of BAI1. Together, these proteins may play a role in cell adhesion and signal transduction.Synonyms: AIP-3, AIP3, Atrophin-1-interacting protein 3, BAI1-associated protein 1, BAP-1, BAP1, MAGI-1, Membrane-associated guanylate kinase, Membrane-associated guanylate kinase inverted 1, TNRC19, Trinucleotide repeat-containing gene 19 protein, WW and PDZ domain-containing protein 1, WWP3
Gene ID 9223
NCBI Accession NP_001028229
UniProt Q96QZ7
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-MAGI1 antibody (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1) (C-Term) (ABIN360704) anti-Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) (C-Term) antibody
 image for anti-MAGI1 antibody (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1) (C-Term) (ABIN360704) anti-Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) (C-Term) antibody (Image 2)
Background publications Patrie, Drescher, Welihinda, Mundel, Margolis: "Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 30183-90, 2002 (PubMed).

Shiratsuchi, Futamura, Oda, Nishimori, Nakamura, Tokino: "Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1." in: Biochemical and biophysical research communications, Vol. 247, Issue 3, pp. 597-604, 1998 (PubMed).

Wood, Yuan, Margolis, Colomer, Duan, Kushi, Kaminsky, Kleiderlein, Sharp, Ross: "Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins." in: Molecular and cellular neurosciences, Vol. 11, Issue 3, pp. 149-60, 1998 (PubMed).

Margolis, Abraham, Gatchell, Li, Kidwai, Breschel, Stine, Callahan, McInnis, Ross: "cDNAs with long CAG trinucleotide repeats from human brain." in: Human genetics, Vol. 100, Issue 1, pp. 114-22, 1997 (PubMed).

Pirozzi, McConnell, Uveges, Carter, Sparks, Kay, Fowlkes: "Identification of novel human WW domain-containing proteins by cloning of ligand targets." in: The Journal of biological chemistry, Vol. 272, Issue 23, pp. 14611-6, 1997 (PubMed).