DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39A (DDX39) antibody

Antigen: DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39A (DDX39)

Synonyms: BAT1, DDXL, BAT1L, URH49, MGC8417, MGC18203

Clonality: Monoclonal (2E4)

Host: Mouse

Reactivity: Human, Rat (Rattus)

Application: ELISA, Immunohistochemistry (IHC)

Catalog no.: ABIN361531

Additional Information

Alternative name: DDX39

Gene ID: 10212

Immunogen: Partial peptide of Human DDX39 (N-terminal)

Format: Affinity-purified

Isotype: IgG1 kappa  (Matching secondary antibodies)

Clone: 2E4

Description: Function: Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus Subcellular location: Nucleus Tissue specificity: Detected in testis, and at lower levels in brain, kidney, lung, thymus, spleen and salivary gland Sequence similarities: Belongs to the DEAD box helicase family. DECD subfamily. Contains 1 helicase ATP-binding domain. Contains 1helicase C-terminal domain.

Application Details

Application Notes: ELISA: 1.0ug/ml. IHC: 3.0ug/ml

Concentration: 0.25 mg/ml

Purification: ProteinG Affinity Purified

Buffer: PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]

Storage: Store below -20 degrees Celsius

Research Area: Cancer

Restrictions: For Research Use only

Images

Rat testis tissue

Publications

Publications: Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Pryor, Tung, Yang et al.: "Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56." in: Nucleic acids research, Vol. 32, Issue 6, pp. 1857-65, 2004 (PubMed).

Sugiura, Sakurai, Nagano: "Intracellular characterization of DDX39, a novel growth-associated RNA helicase." in: Experimental cell research, Vol. 313, Issue 4, pp. 782-90, 2007 (PubMed).