The antibody detects endogenous level of STAT6 only when phosphorylated at tyrosine 641.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen
Peptide sequence around phosphorylation site of pTyr641 (R-G-Y (p) -V-P) derived from Human STAT6. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
D12S1644 antibody, IL-4-STAT antibody, STAT6B antibody, STAT6C antibody, signal transducer and activator of transcription 6 antibody, signal transducer and activator of transcription 6-like antibody, STAT6 antibody, Stat6 antibody, LOC100859543 antibody
Background
Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.