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Phospholipase C gamma 2 antibody (AA 1215-1219)
PLCG2
Reactivity: Human, Rat, Mouse
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Phospholipase C gamma 2 Antibody
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Target
See all Phospholipase C gamma 2 (PLCG2) Antibodies
Phospholipase C gamma 2 (PLCG2)
Binding Specificity
All epitopes for Phospholipase C gamma 2 antibodies
AA 1215-1219
Reactivity
All reactivities for Phospholipase C gamma 2 antibodies
Human, Rat, Mouse
Host
All hosts for Phospholipase C gamma 2 antibodies
Rabbit
Clonality
All clonalities for Phospholipase C gamma 2 antibodies
Polyclonal
Conjugate
All conjugates for Phospholipase C gamma 2 antibodies
This Phospholipase C gamma 2 antibody is un-conjugated
Application
All applications for Phospholipase C gamma 2 antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificity
The antibody detects endogenous level of total PLC-g2 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
Immunogen
Peptide sequence around AA 1215-1219 (F-L-Y-D-T) derived from Human PLCg2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Immunohistochemistry: 1:50-1:100 Immunofluorescence: 1:100-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for Phospholipase C gamma 2
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Target
Phospholipase C gamma 2 (PLCG2)
Alternative Name
PLC-gamma2 (PLCG2 Products )
Synonyms
PLCgamma2 antibody, Plcg-2 antibody, APLAID antibody, FCAS3 antibody, phospholipase C, gamma 2 antibody, phospholipase C gamma 2 antibody, phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody, Plcg2 antibody, PLCG2 antibody
Background
The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Molecular Weight
150 kDa
NCBI Accession
NP_002652
UniProt
P16885
Pathways
RTK Signaling , WNT Signaling , Fc-epsilon Receptor Signaling Pathway , Inositol Metabolic Process , Myometrial Relaxation and Contraction , Toll-Like Receptors Cascades , VEGF Signaling , BCR Signaling
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