The antibody detects endogenous level of total c-Kit protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
Immunogen
Peptide sequence around AA 934-938 (H-I-Y-S-N) derived from Human c-Kit. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)