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Aurora Kinase A (AURKA) (C-Term) antibody

Details for Product No. ABIN374071
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Antigen
Synonyms
AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, AIRK1, AU019385, AW539821, Ark1, Aurora-A, Ayk1, IAK, IAK1, Stk6, ARK-1, Eg2, aik, ark1, aur-a, aura, aurka-a, aurora2, btak, stk15, stk6, s ... show more
AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, AIRK1, AU019385, AW539821, Ark1, Aurora-A, Ayk1, IAK, IAK1, Stk6, ARK-1, Eg2, aik, ark1, aur-a, aura, aurka-a, aurora2, btak, stk15, stk6, stk7, 87A7-9/2, Aur-A, AurA, CG3068, Dmel\\CG3068, aur-A, aurA, ck10, ck[10], l(3)87Ac, l(3)ck10, pEg2, wu:fb37c10, wu:fc02c02, zgc:100912, AURKA, aurka show less
Epitope
C-Term
(30), (25), (12), (7), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(168), (55), (45), (27), (26), (13), (12)
Host
Goat
(126), (44), (11), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(134), (74), (42), (38), (38), (26), (20), (18), (9), (5), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN374071
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide from the C Terminus of the protein sequence according to NP_003591.2.
Sequence C-QNKESASKQS
Specificity This antibody detects Aurora kinase A / AURKA at C-term.
Purification Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
Alternative Name Aurora kinase A
Background Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
Alternate names: AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor- amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6
Gene ID 6790
NCBI Accession NP_003591.2
UniProt O14965
Application Notes Peptide ELISA: Detection limit dilution 1: 128000. Western blot: 0.1-0.3 µg/ml. Approx 45kDa band observed in lysates of cell line HeLa andJurkat lysate (calculated MW of 45.8kDa according to NP_003591.2). In transfected HEK293transiently expressing AURKA a band of approx.48kDa is observed. This band is notobserved in the non-transfected HEK293. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Supplier Images
anti-Aurora Kinase A (AURKA) (C-Term) antibody anti-Aurora Kinase A (AURKA) (C-Term) antibody
anti-Aurora Kinase A (AURKA) (C-Term) antibody (2) anti-Aurora Kinase A (AURKA) (C-Term) antibody (Image 2)
Background publications Zhou, Kuang, Zhong et al.: "Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation." in: Nature genetics, Vol. 20, Issue 2, pp. 189-93, 1998 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN374071
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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