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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) (C-Term) antibody

Details for Product No. ABIN374654, Supplier: Log in to see
Antigen
  • si:ch211-147p17.1
  • P54H
  • Xp54
  • hlr2
  • me31b
  • p54
  • rck
  • HLR2
  • P54
  • RCK
  • p54h
  • RGD1564560
  • 1110001P04Rik
  • E230023J21Rik
  • mRCK/P54
Epitope
C-Term
34
16
15
13
9
6
5
3
2
2
2
2
2
2
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
96
18
16
5
3
2
1
1
1
1
Host
Goat
71
14
11
Clonality
Polyclonal
Conjugate
Un-conjugated
6
5
5
5
5
5
Application
Western Blotting (WB)
89
53
25
10
6
5
2
2
1
1
Supplier
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Immunogen Peptide with sequence C-AEYHSEPVEDEKP, from the C Terminus of the protein sequence
Specificity This antibody reacts to DDX6.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name DDX6 (DDX6 Antibody Abstract)
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis and cellular growth and division. In the process of mRNA degradation, DDX6 may play a role in mRNA decapping. It forms a complex with DCP1A, DCP2, EDC3 and EDC4/HEDLS.Synonyms: ATP-dependent RNA helicase DDX6, ATP-dependent RNA helicase p54, DDX-6, DEAD box protein 6, HLR2, Oncogene RCK, RCK
Gene ID 1656
NCBI Accession NP_004388
UniProt P26196
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) (C-Term) antibody (ABIN374654) anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) (C-Term) antibody
 image for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) (C-Term) antibody (ABIN374654) anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) (C-Term) antibody (Image 2)
Background publications Cougot, Babajko, Séraphin: "Cytoplasmic foci are sites of mRNA decay in human cells." in: The Journal of cell biology, Vol. 165, Issue 1, pp. 31-40, 2004 (PubMed).