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Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (C-Term) antibody

Details for Product No. ABIN374773, Supplier: Login to see
Antigen
  • TREM-A1
  • TREM-B1
  • TREM2
  • trem-2
  • trem2a
  • trem2b
  • trem2c
  • TREM-2
  • Trem2a
  • Trem2b
  • Trem2c
Epitope
C-Term
31
17
16
14
10
8
7
6
3
2
2
1
1
1
1
1
1
1
Reactivity
Human
81
71
18
Host
Goat
62
35
28
10
1
Clonality
Polyclonal
Conjugate
Un-conjugated
11
11
7
7
7
6
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
74
70
25
16
11
9
4
4
3
2
1
1
1
Supplier
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Immunogen Peptide with sequence C-HGQKPGTHPPSELD, from the C Terminus of the protein sequence
Specificity This antibody reacts to TREM2.
Purification Affinity chromatography
Alternative Name TREM2 (TREM2 Antibody Abstract)
Background The protein encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy.Synonyms: TREM-2, Trem2a, Trem2b, Trem2c, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2
Gene ID 54209, 9606
UniProt Q9NZC2
Research Area Immunology, Innate Immunity, Signaling
Pathways
Application Notes Peptide ELISA: 1/32000. Western Blot: 1 μg/mLImmunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (C-Term) antibody (ABIN374773) anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (C-Term) antibody
Background publications Takahashi, Prinz, Stagi et al.: "TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis." in: PLoS medicine, Vol. 4, Issue 4, pp. e124, 2007 (PubMed).