FGF21 antibody (Internal Region)
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- Target See all FGF21 Antibodies
- FGF21 (Fibroblast Growth Factor 21 (FGF21))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This FGF21 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- CQRPDGALYG SLH
- Specificity
- This antibody detects FGF21.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human
- Purification
- ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- Immunogen
- Peptide from the internal region of the protein sequence according to NP_061986.1.
- Top Product
- Discover our top product FGF21 Primary Antibody
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- Application Notes
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Peptide ELISA: limit dilution 1: 2000. Western blot: 1-3 μg/mL. Approx 22 kDa band observed in Human Liver lysates (calculatedMW of 22.2 kDa according to NP_061986.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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Activation of the farnesoid X receptor induces hepatic expression and secretion of fibroblast growth factor 21." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 25123-38, (2012) (PubMed).
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Activation of the farnesoid X receptor induces hepatic expression and secretion of fibroblast growth factor 21." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 25123-38, (2012) (PubMed).
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- Target
- FGF21 (Fibroblast Growth Factor 21 (FGF21))
- Alternative Name
- FGF21 (FGF21 Products)
- Synonyms
- FGF21 antibody, fibroblast growth factor 21 antibody, FGF21 antibody, fgf21 antibody, Fgf21 antibody
- Background
- FGF21 is a growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF21, in the presence of betaKlotho as a protein cofactor, signals through the FGFR 1c and 4 receptors and stimulates insulin independent glucose uptake by adipocytes.Synonyms: FGF-21, Fibroblast growth factor 21
- Gene ID
- 26291, 9606
- UniProt
- Q9NSA1
- Pathways
- RTK Signaling
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