Peptide ELISA: 1/64000. Western Blot: 0.01 - 0.03 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0,5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Nova-1 antibody, NOVA1 antibody, si:ch211-222c22.9 antibody, 9430099M15Rik antibody, G630039L02 antibody, NOVA alternative splicing regulator 1 antibody, neuro-oncological ventral antigen 1 L homeolog antibody, neuro-oncological ventral antigen 1 antibody, RNA-binding protein Nova-1 antibody, lipid A export ATP-binding/permease protein antibody, NOVA1 antibody, Nova1 antibody, nova1.L antibody, nova1 antibody, LOC790874 antibody, novA1 antibody
Background
Nova proteins are splicing factors that are expressed specifically in the central nervous system, where they regulate a large number of pre-mRNAs encoding synaptic proteins. Nova1 is a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer.Synonyms: Neuro-oncological ventral antigen 1, Onconeural ventral antigen 1, Paraneoplastic Ri antigen, RNA-binding protein Nova-1, Ventral neuron-specific protein 1