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PIK3CA antibody (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide) (Internal Region)

Details for Product anti-PIK3CA Antibody No. ABIN375147, Supplier: Login to see
Antigen
  • PI3-kinase
  • PI3K-alpha
  • pi3-k
  • pi3k
  • 6330412C24Rik
  • caPI3K
  • p110
  • p110alpha
  • CLOVE
  • CWS5
  • MCAP
  • MCM
  • MCMTC
  • PI3K
  • p110-alpha
  • C-P3K
Alternatives
anti-Human PIK3CA antibody for ELISA
Epitope
Internal Region
34
16
14
14
13
12
9
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
155
49
42
6
3
2
1
1
1
Host
Goat
114
23
22
Clonality
Polyclonal
Conjugate
This PIK3CA antibody is un-conjugated
7
7
7
6
5
5
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
92
75
68
32
22
11
9
6
4
4
2
2
1
1
Supplier
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Immunogen Peptide with sequence C-HQWLKDKNKGEIYD, from the internal region of the protein sequence
Specificity This antibody reacts to PIK3CA / P110alpha.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Bovine, Canine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name PIK3CA (PIK3CA Antibody Abstract)
Background Synonyms: 5-bisphosphate 3-kinase catalytic subunit alpha isoform, EC=2.7.1.153, PI3-kinase p110 subunit alpha, PI3K, PIK3CA, Phosphatidylinositol-4, PtdIns-3-kinase p110
Gene ID 5290, 9606
UniProt P42336
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes Peptide ELISA: 1/128000. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-PIK3CA antibody (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide) (Internal Region) (ABIN375147) anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Internal Region) antibody
Background publications Abubaker, Bavi, Al-Haqawi et al.: "PIK3CA alterations in Middle Eastern ovarian cancers." in: Molecular cancer, Vol. 8, pp. 51, 2009 (PubMed).