DHX9 antibody (Internal Region)

Catalog No. ABIN375159

Product Details anti-DHX9 Antibody

Target: DHX9 (ATP-Dependent RNA Helicase A (DHX9))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This DHX9 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TEGRNALIHK SSVNC

Specificity: This antibody recognizes DHX9 / RHA.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_001348.2. Genename: DHX9

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DHX9

Target: DHX9 (ATP-Dependent RNA Helicase A (DHX9))

Alternative Name: DHX9 (DHX9 Products)

Synonyms: DDX9 antibody, LKP antibody, NDH2 antibody, NDHII antibody, RHA antibody, AI326842 antibody, Ddx9 antibody, HEL-5 antibody, mHEL-5 antibody, DExH-box helicase 9 antibody, DEAH-box helicase 9 L homeolog antibody, DEAH (Asp-Glu-Ala-His) box polypeptide 9 antibody, DHX9 antibody, dhx9.L antibody, Dhx9 antibody

Background: RNA Helicase A unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alteration of secondary structure may subsequently influence interactions with proteins or other nucleic acids. It functions as a transcriptional activator. It binds MBD2, HRMT1L2/PRMT1, and RELA. It may act to directly link BRCA1, CREBBP or SMN1 and the RNA polymerase II complex. It can also interact with XRCC5 and with TOP2A in a RNA dependent manner, these interactions may be indirect. Interaction with TOP2A is promoted by UBC9 (referenced from swissprot).Synonyms: ATP-dependent RNA helicase A, DDX9, DEAH box protein 9, DHX-9, LKP, NDH II, NDH2, Nuclear DNA helicase II

Gene ID: 1660, 9606

UniProt: Q08211