MUTYH antibody (C-Term)

Catalog No. ABIN375216

This anti-MUTYH antibody is a Goat Polyclonal antibody detecting MUTYH in WB and EIA. Suitable for Human.

Quick Overview for MUTYH antibody (C-Term) (ABIN375216)

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This MUTYH antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-MUTYH Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to MUTYH.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-HISTDAHSLNSAAQ, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MUTYH

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Alternative Name: MUTYH

Background: MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.Synonyms: A/G-specific adenine DNA glycosylase, MYH, MutY homolog

Gene ID: 4595

NCBI Accession: NP_001041636

UniProt: Q9UIF7

Pathways: DNA Damage Repair