EPH Receptor B4 antibody

Catalog No. ABIN387814

This Mouse Monoclonal antibody specifically detects EPH Receptor B4 in WB. It exhibits reactivity toward Human.

Quick Overview for EPH Receptor B4 antibody (ABIN387814)

Target: EPH Receptor B4 (EPHB4)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor B4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 67CT23-5-8

Product Details anti-EPH Receptor B4 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: EPHB4 recombinant protein is used to produce this monoclonal antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:200~2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Alternative Name: EPHB4

Background: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Molecular Weight: 108270

Gene ID: 2050

NCBI Accession: NP_004435

UniProt: P54760

Pathways: RTK Signaling