MAP-2 (C-Term), (AA 1766-1796) antibody

Details for Product No. ABIN388759
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Antigen
Synonyms p67, p67eIF2, MAP2A, MAP2B, MAP2C, MAP-2, Mtap-2, Mtap2, MAP2R, xmap2, MGC53131, a730034c02
Epitope
C-Term, AA 1766-1796
(13), (12), (12), (12), (11), (5), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(162), (100), (99), (77), (36), (24), (19), (4), (3), (3), (3), (1)
Host
Rabbit
(107), (96), (18), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(9), (7), (7), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(157), (68), (54), (53), (49), (45), (30), (30), (26), (21), (10), (3), (2), (2), (1)
Pubmed 3 references available
Quantity 400 µL
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Catalog No. ABIN388759
291.50 $
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Immunogen This MAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1766-1796 AA from the C-terminal region of human MAP2.
Clone RB02868
Isotype Ig
Specificity This MAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418~447 amino acids from the C-terminal region of human MAP2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MAP2
Background This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The exact function of this gene is still unknown. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development.
Synonyms: Microtubule-associated protein 2, MAP-2, MAP2
Molecular Weight 199610 DA
Gene ID 4133
UniProt P11137
Research Area Stem Cells, Signaling, Neurology, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.38 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-MAP-2 (C-Term), (AA 1766-1796) antibody Western blot analysis of hMAP2-Q425 (arrow) using rabbit polyclonal hMAP2-Q425 Antibody (ABIN388759). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the hMAP2-Q425 gene (Lane 2) (Origene Technologies).
anti-MAP-2 (C-Term), (AA 1766-1796) antibody (2) Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with hMAP2-Q425 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistr
Background publications DeTure, Di Noto, Purich: "In vitro assembly of Alzheimer-like filaments. How a small cluster of charged residues in Tau and MAP2 controls filament morphology." in: The Journal of biological chemistry, Vol. 277, Issue 38, pp. 34755-9, 2002 (PubMed).

Al-Bassam, Ozer, Safer et al.: "MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments." in: The Journal of cell biology, Vol. 157, Issue 7, pp. 1187-96, 2002 (PubMed).

Liu, Saad, Shen et al.: "Diagnostic value of microtubule-associated protein-2 (MAP-2) for neuroendocrine neoplasms." in: Advances in anatomic pathology, Vol. 10, Issue 2, pp. 101-6, 2003 (PubMed).

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