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C-JUN antibody (Jun Proto-Oncogene) (pSer63)

Details for Product anti-JUN Antibody No. ABIN389545, Supplier: Log in to see
Antigen
  • BSK
  • BSK/DJNK
  • Bsk
  • CG5680
  • D-JNK
  • D-junk
  • DBSK/JNK
  • DJNK
  • DJNK/bsk
  • Dmel\\CG5680
  • JNK
  • JNK/SAPK
  • Jnk
  • Junk
  • SAPKa
  • c-Jun
  • dJNK
  • jnk
  • Jun
  • AP-1
  • JUN
  • B230310J22Rik
  • p39
  • Junc
  • c-jun
  • AP1
  • fj36h07
  • wu:fj36h07
  • zgc:65863
  • CG2275
  • D-Jun
  • D-jun
  • D-jun/Jra
  • DJUN
  • DJun
  • Djun
  • Dmel\\CG2275
  • JRA
  • V
  • cJun
  • d-JRA
  • d-Jun
  • d-jun
  • dAP-1
  • dJRA
  • dJUN
  • dJra
  • dJun
  • djun
  • dm-Jun
  • jra
  • jun
  • l(2)46Ef
  • l(2)IA109
  • l(2R)IA109
Alternatives
anti-Human C-JUN antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
pSer63
69
57
42
39
39
38
37
34
22
19
19
19
13
13
13
13
11
11
8
8
7
7
6
6
6
5
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
709
378
317
44
36
30
21
17
17
12
11
8
5
5
3
2
2
2
2
1
Host
Rabbit
640
94
2
2
Clonality (Clone)
Polyclonal ()
Conjugate
This C-JUN antibody is un-conjugated
16
16
16
12
9
9
9
7
7
7
7
7
7
7
7
Application
Dot Blot (DB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
551
319
172
99
92
84
67
59
21
20
11
10
8
6
4
3
2
1
1
Supplier
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Immunogen This cJun Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S63 of human cJun.
Clone RB5193
Isotype Ig
Specificity This Phospho-cJun-S63 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S63 of human cJun.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name cJun (JUN Antibody Abstract)
Background The gene for cJun is the putative transforming gene of avian sarcoma virus 17. The cJun protein is a transcription factor highly similar to the viral protein, and interacts directly with specific target DNA sequences to regulate gene expression. The gene maps to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Synonyms: Transcription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN,
Molecular Weight 35676 DA
Gene ID 3725
UniProt P05412
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Pathways MAPK Signaling, RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes DB = 1:500, WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.27 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Dot Blot (DB) image for anti-C-JUN antibody (Jun Proto-Oncogene) (pSer63) (ABIN389545) Dot blot analysis of anti-Phospho-cJun-S63 Antibody (ABIN389545) on nitrocellulose me...
Western Blotting (WB) image for anti-C-JUN antibody (Jun Proto-Oncogene) (pSer63) (ABIN389545) Western blot analysis of anti-Phospho-cJun-pS63 Pab (ABIN389545) in mouse brain tissu...
Immunohistochemistry (IHC) image for anti-C-JUN antibody (Jun Proto-Oncogene) (pSer63) (ABIN389545) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Background publications Cheng, Perkins, Yeh: "Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases." in: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 14492-8, 2005 (PubMed).

Cheung, Acevedo, Cole et al.: "Altered pharmacology and distinct coactivator usage for estrogen receptor-dependent transcription through activating protein-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 3, pp. 559-64, 2005 (PubMed).

Quan, He, Voorhees et al.: "Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8079-85, 2005 (PubMed).

Bladh, Lidén, Dahlman-Wright et al.: "Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-kappaB and activator protein-1 ..." in: Molecular pharmacology, Vol. 67, Issue 3, pp. 815-26, 2005 (PubMed).