Jun Proto-Oncogene (JUN) (pSer63) antibody

Details for Product No. ABIN389545
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Antigen
Synonyms p39, B230310J22Rik, AP1, AP-1, c-Jun, Junc, c-jun, Jun, JUN, fj36h07, zgc:65863, wu:fj36h07
Epitope
pSer63
(71), (60), (55), (45), (38), (35), (29), (19), (15), (13), (11), (9), (8), (7), (6), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(618), (426), (387), (154), (152), (150), (139), (10), (7), (6), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1)
Host
Rabbit
(581), (57), (2), (1), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(16), (16), (16), (12), (12), (12), (12), (12), (12), (12), (12), (4), (4), (4)
Application
Dot Blot (DB), Western Blotting (WB), Immunohistochemistry (IHC)
(480), (232), (204), (128), (119), (68), (49), (42), (21), (8), (8), (8), (2), (1), (1)
Pubmed 4 references available
Catalog no. ABIN389545
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This cJun Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S63 of human cJun.
Clone RB5193
Isotype Ig
Specificity This Phospho-cJun-S63 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S63 of human cJun.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name cJun
Background The gene for cJun is the putative transforming gene of avian sarcoma virus 17. The cJun protein is a transcription factor highly similar to the viral protein, and interacts directly with specific target DNA sequences to regulate gene expression. The gene maps to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Synonyms: Transcription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN,
Molecular Weight 35676 DA
Gene ID 3725
UniProt P05412
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes DB = 1:500, WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.27 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Jun Proto-Oncogene (JUN) (pSer63) antibody Dot blot analysis of anti-Phospho-cJun-S63 Antibody (ABIN389545) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL.
anti-Jun Proto-Oncogene (JUN) (pSer63) antibody (2) Western blot analysis of anti-Phospho-cJun-pS63 Pab (ABIN389545) in mouse brain tissue lysate (35 µg/lane). Mouse Phospho-cJun-pS63(arrow) was detected using the purified polyclonal antibody.
anti-Jun Proto-Oncogene (JUN) (pSer63) antibody (3) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma
Background publications Bladh, Lidén, Dahlman-Wright et al.: "Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-kappaB and activator protein-1 repression." in: Molecular pharmacology, Vol. 67, Issue 3, pp. 815-26, 2005 (PubMed).

Quan, He, Voorhees et al.: "Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8079-85, 2005 (PubMed).

Cheung, Acevedo, Cole et al.: "Altered pharmacology and distinct coactivator usage for estrogen receptor-dependent transcription through activating protein-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 3, pp. 559-64, 2005 (PubMed).

Cheng, Perkins, Yeh: "Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases." in: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 14492-8, 2005 (PubMed).

Hosts (581), (57), (2), (1), (1)
Reactivities (618), (426), (387), (154), (152), (150), (139), (10), (7), (6), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1)
Applications (480), (232), (204), (128), (119), (68), (49), (42), (21), (8), (8), (8), (2), (1), (1)
Conjugates (16), (16), (16), (12), (12), (12), (12), (12), (12), (12), (12), (4), (4), (4)
Epitopes (71), (60), (55), (45), (38), (35), (29), (19), (15), (13), (11), (9), (8), (7), (6), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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