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Aminolevulinate Dehydratase (ALAD) (AA 244-272), (C-Term) antibody

Details for Product No. ABIN390809, Supplier: Log in to see
Antigen
  • DDBDRAFT_0190269
  • DDBDRAFT_0231415
  • DDB_0190269
  • DDB_0231415
  • ALAD
  • ncf
  • ALADH
  • PBGS
  • ALADR
  • aminolevulinatedelta-dehydratase
  • zgc:110219
  • Lv
Epitope
AA 244-272, C-Term
11
5
5
3
2
2
2
1
1
1
1
Reactivity
Human
50
18
18
3
3
1
1
Host
Rabbit
48
5
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
38
11
9
7
6
3
2
2
1
Supplier
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Immunogen This ALAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244-272 AA from the C-terminal region of human ALAD.
Clone RB20913
Isotype Ig
Specificity This ALAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251~280 amino acids from the C-terminal region of human ALAD.
Predicted Reactivity Monkey
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name ALAD (ALAD Antibody Abstract)
Background The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.
Synonyms: Delta-aminolevulinic acid dehydratase, ALADH, Porphobilinogen synthase, ALAD
Molecular Weight 36295 DA
Gene ID 210
UniProt P13716
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Aminolevulinate Dehydratase (ALAD) (AA 244-272), (C-Term) antibody (ABIN390809) Western blot analysis of ALAD Antibody (C-term) (ABIN390809) in Jurkat cell line lysa...
Immunohistochemistry (IHC) image for anti-Aminolevulinate Dehydratase (ALAD) (AA 244-272), (C-Term) antibody (ABIN390809) Formalin-fixed and paraffin-embedded human brain tissue reacted with ALAD Antibody (C...
Flow Cytometry (FACS) image for anti-Aminolevulinate Dehydratase (ALAD) (AA 244-272), (C-Term) antibody (ABIN390809) ALAD Antibody (C-term) (ABIN390809) flow cytometric analysis of Jurkat cells (right h...
Background publications Guey, García-Closas, Murta-Nascimento et al.: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, 2010 (PubMed).