This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This COL4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human COL4A1.
COL4A1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IF: 1:25. WB: 1:1000. WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Chou, Chuang, Lu, Guh: "Vitamin D-binding protein is required for the protective effects of vitamin D in renal fibroblasts and is phosphorylated in diabetic rats." in: Molecular and cellular endocrinology, Vol. 411, pp. 67-74, (2015) (PubMed).
Tiao, Wang, Huang, Chuang, Kuo, Yang, Huang: "MicroRNA-29a protects against acute liver injury in a mouse model of obstructive jaundice via inhibition of the extrinsic apoptosis pathway." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 1, pp. 30-41, (2014) (PubMed).
Yao, Yang, Liu, Tan, Lu, Yuan, Ma: "Follicle-stimulating hormone regulation of microRNA expression on progesterone production in cultured rat granulosa cells." in: Endocrine, Vol. 38, Issue 2, pp. 158-66, (2010) (PubMed).
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Background
COL4A1 is the major type IV alpha collagen chain of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter.