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Vinculin antibody (C-Term)
VCL
Reactivity: Human, Mouse
WB
Host: Rabbit
Polyclonal
RB16690
unconjugated
Product Details anti-Vinculin Antibody
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Target
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Vinculin (VCL)
Binding Specificity
All epitopes for Vinculin antibodies
AA 1012-1039, C-Term
Reactivity
All reactivities for Vinculin antibodies
Human, Mouse
Host
All hosts for Vinculin antibodies
Rabbit
Clonality
All clonalities for Vinculin antibodies
Polyclonal
Conjugate
All conjugates for Vinculin antibodies
This Vinculin antibody is un-conjugated
Application
All applications for Vinculin antibodies
Western Blotting (WB)
Predicted Reactivity
C, Pig, Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This VINC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1012-1039 amino acids from the C-terminal region of human VINC.
Clone
RB16690
Isotype
Ig Fraction
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Discover our top product VCL Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:1000. WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for Vinculin
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Target
Vinculin (VCL)
Alternative Name
Vinculin (VCL Products )
Synonyms
CMD1W antibody, CMH15 antibody, MV antibody, MVCL antibody, VCL antibody, im:6902790 antibody, hm:zehn2160 antibody, DDBDRAFT_0186762 antibody, DDBDRAFT_0232320 antibody, DDB_0186762 antibody, DDB_0232320 antibody, 9430097D22 antibody, AA571387 antibody, AI462105 antibody, AW545629 antibody, CG3299 antibody, CT11081 antibody, Dmel\\CG3299 antibody, Dmvincp antibody, EG:103B4.1 antibody, Vin antibody, Vin2EF antibody, vinc antibody, LOC100228062 antibody, vcl-A antibody, vinculin antibody, vinculin a antibody, vinculin A antibody, Vinculin antibody, vinculin S homeolog antibody, VCL antibody, vcla antibody, vinA antibody, Vcl antibody, Vinc antibody, CpipJ_CPIJ013873 antibody, Bm1_37935 antibody, vcl antibody, vcl.S antibody
Background
VINC is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia.
Molecular Weight
123799
Gene ID
7414
NCBI Accession
NP_003364 , NP_054706
UniProt
P18206
Pathways
Cell-Cell Junction Organization , Maintenance of Protein Location , Signaling Events mediated by VEGFR1 and VEGFR2
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