You are viewing an incomplete version of our website. Please click to reload the website as full version.

ERBB4 antibody (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian)) (AA 1276-1308)

Details for Product anti-ERBB4 Antibody No. ABIN391951, Supplier: Login to see
Antigen
  • erbb4
  • si:ch211-227n20.1
  • Her4
  • c-erbB-4
  • HER4
  • p180erbB4
Alternatives
anti-Human ERBB4 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 1276-1308, C-Term
64
31
29
29
21
18
17
14
14
13
7
7
6
5
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
315
119
111
3
3
2
2
1
1
1
1
1
1
1
1
1
Host
Rabbit
281
37
Clonality (Clone)
Polyclonal ()
Conjugate
This ERBB4 antibody is un-conjugated
19
16
15
12
11
10
8
5
5
5
5
5
5
5
5
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
165
105
105
61
60
29
26
22
16
3
2
2
1
1
1
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This ERBB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1276-1308 AA from the C-terminal region of human ERBB4.
Clone RB01472
Isotype Ig
Specificity This ErbB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1279~1308 amino acids from the C-terminal region of human ErbB4.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name ErbB4 (ERBB4 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Synonyms: Tyrosine kinase-type cell surface receptor HER4, HER4
Molecular Weight 147000 DA
Gene ID 2066
UniProt Q15303
Research Area Phospho-specific antibodies, Stem Cells, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ERBB4 antibody (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian)) (AA 1276-1308) (ABIN391951) Western blot analysis of anti-ErbB4 Pab (ABIN391951) in T-47D cell lysate. ErbB4 (arr...
Immunohistochemistry (IHC) image for anti-ERBB4 antibody (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian)) (AA 1276-1308) (ABIN391951) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Background publications Cheng, Tikhomirov, Zhou et al.: "Ectodomain cleavage of ErbB-4: characterization of the cleavage site and m80 fragment." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38421-7, 2003 (PubMed).

Komuro, Nagai, Navin et al.: "WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus." in: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 33334-41, 2003 (PubMed).

Ni, Yuan, Carpenter: "Role of the ErbB-4 carboxyl terminus in gamma-secretase cleavage." in: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 4561-5, 2003 (PubMed).

Did you look for something else?