Sestrin 1 (SESN1) (AA 312-341), (C-Term) antibody

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Antigen
Synonyms zgc:91970, sestrin-1, SESN1, XPA26, pa26, sest1, PA26, SEST1, 1110002G11Rik, AU044290, Pa26, Sest1, sesn1-A
Epitope
AA 312-341, C-Term
(6), (5), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(51), (32), (23)
Host
Rabbit
(50), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS), Western Blotting (WB)
(43), (19), (11), (8), (5), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Quantity 400 μL
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Immunogen This Sestrin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 AA from the C-terminal region of human Sestrin-1.
Clone RB18601
Isotype Ig
Specificity This Sestrin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319~349 amino acids from the C-terminal region of human Sestrin-1.
Predicted Reactivity Monkey,Xenopus laevis
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Sestrin-1 (SESN1 Antibody Abstract)
Background Sestrin-1 is involved in the reduction of peroxiredoxins. This protein may also be regulator of cellular growth.
Synonyms: Sestrin-1, p53-regulated protein PA26, SEST1, PA26, SESN1
Molecular Weight 56557 DA
Gene ID 27244
UniProt Q9Y6P5
Research Area Cell Cycle, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Sestrin 1 (SESN1) (AA 312-341), (C-Term) antibody (ABIN391992) Western blot analysis of Sestrin-1 antibody (C-term) (ABIN391992) in mouse heart tiss...
Western Blotting (WB) image for anti-Sestrin 1 (SESN1) (AA 312-341), (C-Term) antibody (ABIN391992) Sestrin-1 Antibody (C-term) (ABIN391992) western blot analysis in NCI-H460,HL-60 cell...
Flow Cytometry (FACS) image for anti-Sestrin 1 (SESN1) (AA 312-341), (C-Term) antibody (ABIN391992) Sestrin-1 Antibody (C-term) (ABIN391992) flow cytometric analysis of NCI-H460 cells (...
Background publications Budanov, Sablina, Feinstein et al.: "Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD." in: Science (New York, N.Y.), Vol. 304, Issue 5670, pp. 596-600, 2004 (PubMed).

Peeters, Debeer, Bairoch et al.: "PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene family in human and mouse." in: Human genetics, Vol. 112, Issue 5-6, pp. 573-80, 2003 (PubMed).

Velasco-Miguel, Buckbinder, Jean et al.: "PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes." in: Oncogene, Vol. 18, Issue 1, pp. 127-37, 1999 (PubMed).

Catalog No. ABIN391992
$324.50
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Plus shipping costs $45.00

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