KIT antibody (N-Term)

Catalog No. ABIN392008

This Rabbit Polyclonal antibody specifically detects KIT in WB. It exhibits reactivity toward Human and Monkey.It has been mentioned in 1 publication

Quick Overview for KIT antibody (N-Term) (ABIN392008)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIT antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB1558

Product Details anti-KIT Antibody

Binding Specificity: AA 9-40, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This c-KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-40 amino acids from the N-terminal region of human c-KIT.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-KIT antibody (ABIN392008)

Wright, Robles, Herschkowitz, Hollingshead, Anver, Perou, Varticovski: "Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1." in: Molecular cancer, Vol. 7, pp. 29, (2008) (PubMed).

Target Details for KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Alternative Name: c-KIT

Background: KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

Molecular Weight: 109865

Gene ID: 3815

NCBI Accession: NP_000213, NP_001087241

UniProt: P10721

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity