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RIPK2 antibody (Receptor-Interacting Serine-threonine Kinase 2) (AA 458-488)

Details for Product anti-RIPK2 Antibody No. ABIN392274, Supplier: Login to see
Antigen
  • RIPK2
  • 2210420D18Rik
  • CARD3
  • CARDIAK
  • CCK
  • D4Bwg0615e
  • RICK
  • RIP2
  • GIG30
Alternatives
anti-Human RIPK2 antibody for Western Blotting
Epitope
AA 458-488, C-Term
30
19
10
9
5
5
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
143
35
22
4
4
2
2
2
Host
Rabbit
122
16
5
Clonality (Clone)
Polyclonal ()
Conjugate
This RIPK2 antibody is un-conjugated
6
5
4
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
130
70
40
20
16
13
3
3
3
2
1
Supplier
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Immunogen This RIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-488 AA from the C-terminal region of human RIPK2.
Clone RB03318
Isotype Ig
Specificity This RIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467~496 amino acids from the C-terminal region of human RIPK2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name RIPK2 (RIPK2 Antibody Abstract)
Background RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
Synonyms: Receptor-interacting serine/threonine protein kinase 2, RIP-like interacting CLARP kinase, Receptor-interacting protein 2, RIP-2, CARD-containing interleukin-1 beta converting enzyme associated kinase, CARD-containing IL-1 beta ICE-kinase, RIP2
Molecular Weight 61194 DA
Gene ID 8767
NCBI Accession NP_003812
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Pathways TCR Signaling, Neurotrophin Signaling Pathway
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-RIPK2 antibody (Receptor-Interacting Serine-threonine Kinase 2) (AA 458-488) (ABIN392274) Western blot analysis of anti-RIPK2 Pab (ABIN392274) in Ramos cell line lysates (35 µ...
Western Blotting (WB) image for anti-RIPK2 antibody (Receptor-Interacting Serine-threonine Kinase 2) (AA 458-488) (ABIN392274) Western blot analysis of anti-RIPK2 Pab (ABIN392274) in mouse cerebellum tissue lysat...
Immunohistochemistry (IHC) image for anti-RIPK2 antibody (Receptor-Interacting Serine-threonine Kinase 2) (AA 458-488) (ABIN392274) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Background publications Chen, Clark: "Equilibrium and kinetic folding of an alpha-helical Greek key protein domain: caspase recruitment domain (CARD) of RICK." in: Biochemistry, Vol. 42, Issue 20, pp. 6310-20, 2003 (PubMed).

Munz, Hildt, Springer et al.: "RIP2, a checkpoint in myogenic differentiation." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5879-86, 2002 (PubMed).

Chin, Dempsey, Bruhn et al.: "Involvement of receptor-interacting protein 2 in innate and adaptive immune responses." in: Nature, Vol. 416, Issue 6877, pp. 190-4, 2002 (PubMed).