anti-RIPK2 antibody (Receptor-Interacting Serine-threonine Kinase 2) (AA 458-488)

Details for Product anti-RIPK2 Antibody No. ABIN392274, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms RIPK2, 2210420D18Rik, CARD3, CARDIAK, CCK, D4Bwg0615e, RICK, RIP2, GIG30
Alternatives
Epitope
AA 458-488, C-Term
(30), (19), (11), (10), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(146), (38), (22), (4), (4), (2), (2), (2)
Host
Rabbit
(125), (16), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
This RIPK2 antibody is un-conjugated
(6), (5), (4), (2), (2), (2)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(133), (72), (43), (20), (16), (13), (3), (3), (3), (2), (1)
Pubmed 3 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 400 μL
Options
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This RIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-488 AA from the C-terminal region of human RIPK2.
Clone RB03318
Isotype Ig
Specificity This RIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467~496 amino acids from the C-terminal region of human RIPK2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name RIPK2 (RIPK2 Antibody Abstract)
Background RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
Synonyms: Receptor-interacting serine/threonine protein kinase 2, RIP-like interacting CLARP kinase, Receptor-interacting protein 2, RIP-2, CARD-containing interleukin-1 beta converting enzyme associated kinase, CARD-containing IL-1 beta ICE-kinase, RIP2
Molecular Weight 61194 DA
Gene ID 8767
NCBI Accession NP_003812
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Pathways TCR Signaling, Neurotrophin Signaling Pathway
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-RIPK2 antibody (Receptor-Interacting Serine-threonine Kinase 2) (AA 458-488) (ABIN392274) Western blot analysis of anti-RIPK2 Pab (ABIN392274) in Ramos cell line lysates (35 µ...
Western Blotting (WB) image for anti-RIPK2 antibody (Receptor-Interacting Serine-threonine Kinase 2) (AA 458-488) (ABIN392274) Western blot analysis of anti-RIPK2 Pab (ABIN392274) in mouse cerebellum tissue lysat...
Immunohistochemistry (IHC) image for anti-RIPK2 antibody (Receptor-Interacting Serine-threonine Kinase 2) (AA 458-488) (ABIN392274) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Background publications Chen, Clark: "Equilibrium and kinetic folding of an alpha-helical Greek key protein domain: caspase recruitment domain (CARD) of RICK." in: Biochemistry, Vol. 42, Issue 20, pp. 6310-20, 2003 (PubMed).

Munz, Hildt, Springer et al.: "RIP2, a checkpoint in myogenic differentiation." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5879-86, 2002 (PubMed).

Chin, Dempsey, Bruhn et al.: "Involvement of receptor-interacting protein 2 in innate and adaptive immune responses." in: Nature, Vol. 416, Issue 6877, pp. 190-4, 2002 (PubMed).

Catalog No. ABIN392274
$324.50
Plus shipping costs $45.00
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)