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MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) (AA 600-630), (C-Term) antibody

Details for Product No. ABIN392538, Supplier: Log in to see
Antigen
  • EMK-1
  • EMK1
  • PAR-1
  • Par-1b
  • Par1b
  • AU024026
  • Emk
  • Par-1
  • mKIAA4207
Epitope
AA 600-630, C-Term
26
10
8
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
87
36
32
5
3
1
Host
Rabbit
69
14
5
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
3
3
3
3
3
3
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
70
63
34
25
8
4
3
2
2
1
Supplier
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Immunogen This MARK2 (EMK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 600-630 AA from the C-terminal region of human MARK2 (EMK).
Clone RB2527-2528
Isotype Ig
Specificity This MARK2 (EMK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 574~603 amino acids from the C-terminal region of human EMK.
Predicted Reactivity Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MARK2 (EMK) (MARK2 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Synonyms: Serine/threonine protein kinase
Molecular Weight 83204 DA
Gene ID 2011
UniProt Q15524
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) (AA 600-630), (C-Term) antibody (ABIN392538) Western blot analysis of anti-EMK Antibody (C-term)(ABIN392538) in mouse thymus tissu...
Immunohistochemistry (IHC) image for anti-MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) (AA 600-630), (C-Term) antibody (ABIN392538) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) (AA 600-630), (C-Term) antibody (ABIN392538) EMK Antibody (V581) (ABIN392538) western blot analysis in Ramos cell line lysates (35...
Product cited in: Yoshiike, Yamashita, Mizoroki et al.: "Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes." in: Aging cell, Vol. 11, Issue 1, pp. 51-62, 2012 (PubMed).

Background publications Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, 2001 (PubMed).