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Details for Product No. ABIN392643

Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 271-300), (Center) antibody

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Antigen
Synonyms MLTK, RGD1561394, AZK, MLK7, MLT, MRK, mlklak, pk, AV006891, B230120H23Rik, MLTKalpha, MLTKbeta
Epitope
»Alternatives AA 271-300, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN392643
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This MLKLAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 AA from the Central region of human MLKLAK.
Clone RB03313-03314
Isotype Ig
Specificity This MLKLAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277~307 amino acids from the center region of human MLKLAK.
Predicted Reactivity Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name MLKLAK
Background MLKLAK is a member of the MAPKKK family of signal transduction molecules. It possesses an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity.
Synonyms: Plaucible mixed-lineage kinase protein
Molecular Weight 50000 DA
Gene ID 51776
UniProt NP_598407
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, 2001 (PubMed).

Alternatives for antigen "Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK)", type "Antibodies"
Hosts (34), (11)
Reactivities (45), (23), (13), (12), (12), (12), (12)
Applications (35), (28), (11), (10), (9), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (2), (2), (1), (1), (1)
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