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ZAK antibody
ZAK
Reactivity: Human, Mouse, Rat
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ZAK Antibody
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Target
See all ZAK Antibodies
ZAK
(Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
Reactivity
All reactivities for ZAK antibodies
Human, Mouse, Rat
Host
All hosts for ZAK antibodies
Rabbit
Clonality
All clonalities for ZAK antibodies
Polyclonal
Conjugate
All conjugates for ZAK antibodies
This ZAK antibody is un-conjugated
Application
All applications for ZAK antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human ZAK (NP_598407.1).
Isotype
IgG
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Discover our top product ZAK Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200 IF 1:20-1:50
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for ZAK
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Target
ZAK
(Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
Alternative Name
ZAK (ZAK Products )
Synonyms
MLTK antibody, RGD1561394 antibody, AZK antibody, MLK7 antibody, MLT antibody, MRK antibody, mlklak antibody, pk antibody, AV006891 antibody, B230120H23Rik antibody, MLTKalpha antibody, MLTKbeta antibody, mitogen-activated protein kinase kinase kinase 20 antibody, Map3k20 antibody, MAP3K20 antibody
Background
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
51776
UniProt
Q9NYL2
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