Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3) (AA 1-30), (N-Term) antibody

Details for Product No. ABIN392668, Supplier: Log in to see
Antigen
  • Pacsin1
  • wu:fa11d03
  • wu:fj67e09
  • wu:fq16a06
  • zgc:56324
  • MGC82145
  • PACSIN3
  • sdpiii
  • SDPIII
  • 4921507A02Rik
  • 6330413E15Rik
  • AW413130
  • SdpIII
  • protein kinase C and casein kinase substrate in neurons 3
  • pacsin3
  • PACSIN3
  • Pacsin3
Epitope
AA 1-30, N-Term
32
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
98
38
37
15
14
3
3
3
2
2
1
1
1
Host
Rabbit
51
33
16
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
82
33
32
26
13
11
3
3
2
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen This PACSIN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human PACSIN3.
Clone RB3577
Isotype Ig
Specificity This PACSIN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human PACSIN3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name PACSIN3 (PACSIN3 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
Synonyms: Protein kinase C and casein kinase substrate in neurons protein 3, SH3 domain-containing protein 6511, Endophilin I
Molecular Weight 48486 DA
Gene ID 29763
UniProt Q9UKS6
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Cell Cycle, Transcription Factors, Signaling, Metabolism
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3) (AA 1-30), (N-Term) antibody (ABIN392668) The anti-PACSIN3 Pab (ABIN392668) is used in Western blot to detect PACSIN3 in mouse ...
Immunohistochemistry (IHC) image for anti-Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3) (AA 1-30), (N-Term) antibody (ABIN392668) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3) (AA 1-30), (N-Term) antibody (ABIN392668) PACSIN3 Antibody (M1) (ABIN392668) western blot analysis in 293 cell line lysates (35...
Background publications Howard, Nelson, Maciewicz, Blobel: "Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31693-9, 1999 (PubMed).

Did you look for something else?