ICOSLG antibody

Catalog No. ABIN400712

Product Details anti-ICOSLG Antibody

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICOSLG antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to Inducible T-cell Co-stimulator Ligand (CD275/ICOS Ligand).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: B7 homolog 2, B7-like protein Gl50, B7-related protein 1, ICOSLG, B7H2, B7RP1, B7RP-1,ICOSL, KIAA0653

Purification: Affinity Chromatography.

Immunogen: Recombinant protein Human B7H2-mIg fusion protein.

Clone: 2D3

Isotype: IgG2b

Application Details

Application Notes: ELISA. Flow Cytometry. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 1/50. This CD275/ICOS Ligand antibody was validated for use in immunohistochemistry on apanel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat inducedantigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slideswere incubated with biotinylated secondary antibody LS-D2, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Alternative Name: CD275 / ICOS Ligand (ICOSLG Products)

Synonyms: ICOSLG antibody, AU044799 antibody, B7-H2 antibody, B7RP-1 antibody, B7h antibody, BG071784 antibody, GI50 antibody, GL50 antibody, GL50-B antibody, ICOS-L antibody, Icoslg antibody, LICOS antibody, Ly115l antibody, mKIAA0653 antibody, B7H2 antibody, B7RP1 antibody, CD275 antibody, ICOSL antibody, Icosl antibody, RGD1562791 antibody, inducible T-cell costimulator ligand antibody, icos ligand antibody, inducible T-cell co-stimulator ligand antibody, ICOSLG antibody, Icosl antibody, Icoslg antibody

Background: ICOS ligand (inducible T cell co stimulator ligand) is a member of the B7 family and the immunoglobulin superfamily. Human ICOS ligand is expressed by activated monocytes/macrophages and dendritic cells. It binds to a CD28 like receptor, inducible costimulator molecule (ICOS, AILIM, CRP-1), which is expressed by activated T cells. This interaction plays an important role in the T cell costimulation pathway.Synonyms: B7 homolog 2, B7-like protein Gl50, B7-related protein 1, B7H2, B7RP-1, B7RP1, ICOSL, ICOSLG, KIAA0653

Gene ID: 23308

UniProt: O75144

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation