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CHEK1 antibody (AA 312-327)

The Rabbit Polyclonal anti-CHEK1 antibody is suitable to detect CHEK1 in samples from Saccharomyces cerevisiae. It has been validated for WB and EIA.
Catalog No. ABIN401324
$1,116.00
Plus shipping costs $50.00
0.1 mg
Shipping to: United States
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Quick Overview for CHEK1 antibody (AA 312-327) (ABIN401324)

Target

See all CHEK1 Antibodies
CHEK1 (Checkpoint Kinase 1 (CHEK1))

Reactivity

  • 229
  • 132
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Saccharomyces cerevisiae

Host

  • 241
  • 15
  • 5
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Rabbit

Clonality

  • 192
  • 73
Polyclonal

Conjugate

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  • 15
  • 9
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This CHEK1 antibody is un-conjugated

Application

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  • 87
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  • 22
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Binding Specificity

    • 38
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    • 20
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    • 18
    • 7
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    • 2
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    AA 312-327

    Specificity

    This antibody is directed against yeast CHK1 protein.

    Purification

    Affinity chromatography

    Immunogen

    Synthetic peptide corresponding aa 312-327 of S. cerevisiae CHK1

    Isotype

    IgG
  • Application Notes

    ELISA: 1/2,000 - 1/10,000. Western Blot: 1/200 - 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    0.73 mg/mL (by UV absorbance at 280 nm)

    Buffer

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    -20 °C
  • Target

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    Alternative Name

    CHK1

    Background

    CHK1 (also known as serine/threonine-protein kinase CHK1 and checkpoint kinase 1) is involved in cell cycle arrest when DNA damage has occurred or when unligated DNA is present. The kinase controls phosphorylation and abundance of PDS1 to prevent anaphase entry. Also helps prevent mitotic exit. CHK1 is localized within the nucleus.Synonyms: CHEK-1, CHEK1, CHK1 checkpoint homolog, Serine/threonine-protein kinase Chk1

    Gene ID

    852577

    NCBI Accession

    NP_009833

    UniProt

    P38147

    Pathways

    p53 Signaling, Apoptosis, Cell Division Cycle, DNA Damage Repair
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