GPRC6A antibody (Extracellular Domain, N-Term)

Catalog No. ABIN437963

Product Details anti-GPRC6A Antibody

Target: GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))

Binding Specificity: Extracellular Domain, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPRC6A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: affinity purified

Immunogen: KLH conjugated synthetic peptide- N-terminal extracellular domain of human GPRC6A.

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

Target Details for GPRC6A

Target: GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))

Alternative Name: GPRC6A (GPRC6A Products)

Synonyms: gpcr antibody, GPCR antibody, bA86F4.3 antibody, G protein-coupled receptor class C group 6 member A antibody, G protein-coupled receptor, family C, group 6, member A antibody, G protein-coupled receptor, class C, group 6, member A antibody, GPRC6A antibody, gprc6a antibody, Gprc6a antibody

Background: GPR3, GPR6, and GPR12 make up a family of constitutively active G protein-coupled receptors (GPCRs) that share greater than 50% identity and 65% similarity at the amino acid level and are highly expressed in hippocampus and cortex, regions of the brain . They upregulate cyclic AMP Levels and Promotes Neurite Outgrowth. GPR3 has been mapped to a chromosomal locus associated with increased risk for Alzheimers disease. GPR3 is believed be a factor in accumulation of beta-amyloid (a protein believed to cause the disease).