Factor VII antibody

Catalog No. ABIN452653

Product Details anti-Factor VII Antibody

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Factor VII antibody is un-conjugated

Application: Western Blotting (WB), Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)

Specificity: Recognizes Human Factor VII antigen. Other spcies not tested.

Characteristics: Synonyms: Proconvertin, SPCA, Serum prothrombin conversion accelerator

Purification: Affinity Chromatography on Protein G.

Immunogen: Purified Factor VII.

Clone: RFFVII-2

Isotype: IgG1

Application Details

Application Notes: ELISA. Clone RFFVII/2 may be used as a Capture antibody in Immunoassay for Factor VII incombination with clone RFFVII/1 as a Detection reagent. Radioimmunoassays. Western blotting: This Factor VII antibody binds to a conformational epitope and will notbind to reduced Factor VI.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Abstract: F7 Products

Synonyms: F7 antibody, wu:fb59f04 antibody, zgc:109870 antibody, SPCA antibody, AI114908 antibody, ATIII antibody, At-3 antibody, At3 antibody, LOC100223776 antibody, AI132620 antibody, Cf7 antibody, FVII antibody, mfVII antibody, f7 antibody, coagulation factor VII antibody, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 antibody, coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog antibody, F7 antibody, f7 antibody, Serpinc1 antibody, CpipJ_CPIJ009142 antibody, CpipJ_CPIJ010295 antibody, CpipJ_CPIJ020127 antibody, fa7 antibody, f7.S antibody

Background: Factor VII is a 50 kDa multi-domain, single chain plasma glycoprotein synthesised in the liver and having anormal circulating concentration of between 400 and 600 μg/L. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa through cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts Prothrombin to Thrombin.Synonyms: Proconvertin, SPCA, Serum prothrombin conversion accelerator

Gene ID: 2155

UniProt: P08709

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling