Factor VII antibody

Catalog No. ABIN481753

Product Details anti-Factor VII Antibody

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This Factor VII antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: It is specific for F. VII as determined by immunodiffusion. Identity was established with purified F. VII.

Purification: Ammonium sulfate precipitation

Immunogen: Human Factor VII (F. VII) purified from plasma.

Isotype: IgG

Application Details

Application Notes: Approved: ELISA, IHC, IHC-P (5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. Neutralization: Suitable for use in Immunodepletion Procedures and Neutralization Studies.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: HEPES-buffered saline,  pH 7.4, 50 % glycerol. No preservatives are added.

Preservative: Without preservative

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Alternative Name: F7 / Factor VII (F7 Products)

Synonyms: F7 antibody, wu:fb59f04 antibody, zgc:109870 antibody, SPCA antibody, AI114908 antibody, ATIII antibody, At-3 antibody, At3 antibody, LOC100223776 antibody, AI132620 antibody, Cf7 antibody, FVII antibody, mfVII antibody, f7 antibody, coagulation factor VII antibody, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 antibody, coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog antibody, F7 antibody, f7 antibody, Serpinc1 antibody, CpipJ_CPIJ009142 antibody, CpipJ_CPIJ010295 antibody, CpipJ_CPIJ020127 antibody, fa7 antibody, f7.S antibody

Background: Name/Gene ID: F7
Subfamily: Serine S1
Family: Protease

Synonyms: F7, Coagulation factor VII, Eptacog alfa, F7 Deficiency, Factor 7, Factor VIIa, FVII coagulation protein, Factor VII, FVII, SPCA, Factor VII Deficiency, Proconvertin

Gene ID: 2155

UniProt: P08709

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling