KRT18 antibody (Keratin 18) (C-Term)

Details for Product anti-KRT18 Antibody No. ABIN452897, Supplier: Log in to see
Antigen
  • krt18
  • MGC64569
  • MGC75922
  • KRT18
  • CYK18
  • K18
  • CK18
  • Krt1-18
  • DreK18
  • cb83
  • dapk1
  • sb:cb83
  • wu:fa13f02
  • wu:fb36b04
  • krtt1c6
  • zgc:66015
  • keratin 18
  • similar to Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18)
  • Keratin, type I cytoskeletal 18
  • cytokeratin 18
  • K18, simple type I keratin
  • zgc:77517
  • krt18
  • KRT18
  • k1c18
  • LOC100008885
  • LOC100136778
  • Krt18
  • zgc:77517
Alternatives
anti-Human KRT18 antibody for Immunohistochemistry (Frozen Sections)
Epitope
C-Term
51
36
27
23
20
16
15
11
11
10
9
8
7
6
5
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
947
199
171
71
65
41
36
34
27
27
23
20
18
15
12
7
7
5
5
4
3
3
2
2
1
1
1
Host
Rabbit
699
274
12
11
4
3
2
Clonality
Polyclonal
Conjugate
This KRT18 antibody is un-conjugated
52
48
22
18
17
17
14
14
14
14
14
14
14
14
14
11
11
8
4
3
3
3
3
3
3
3
3
2
2
2
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
655
467
389
349
331
300
225
180
125
40
26
18
18
14
10
9
3
2
2
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human CYK18
Specificity This antibody detects Cytokeratin-18 (KRT18) at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name Cytokeratin 18 (KRT18 Antibody Abstract)
Background KRT18 is the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament family. They are expressed in single layer epithelial tissues of the body. Mutations in its gene have been linked to cryptogenic cirrhosis.Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
Molecular Weight 48058 Da
Gene ID 3875
NCBI Accession NP_000215
UniProt P05783
Research Area Signaling, Cytoskeleton, Extracellular Matrix
Pathways Apoptosis, Caspase Cascade in Apoptosis
Application Notes Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Keratin 18 (KRT18) (C-Term) antibody (ABIN452897) anti-Keratin 18 (KRT18) (C-Term) antibody
Background publications Zhang, Helfand, Jang, Zhu, Chen, Yang, Kozlowski, Smith, Kundu, Yang, Raji, Javonovic, Pins, Lindholm, Guo, Catalona, Lee: "Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 10, pp. 3557-67, 2009 (PubMed).

Kruse, Eigelshoven, Kaiser, Ruzicka, Neumann: "Cytokeratin 18 expression in immature Sertoli cells: co-localization with interstitial lymphocytic infiltrates." in: Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society, Vol. 47, Issue 1, pp. 127-30, 2009 (PubMed).