SRP72 antibody (Signal Recognition Particle 72kDa) (AA 126-156)

Details for Product anti-SRP72 Antibody No. ABIN453397, Supplier: Log in to see
Antigen
  • CG5434
  • Dmel\\CG5434
  • wu:fi03d11
  • 5730576P14Rik
  • 72kDa
  • AI132477
  • BC019196
  • C77589
  • BMFF
  • Signal recognition particle protein 72
  • signal recognition particle 72kDa
  • signal recognition particle subunit Srp72
  • part of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex
  • type II secretory pathway family
  • signal recognition particle 72
  • Srp72
  • SRP72
  • srp72
Epitope
AA 126-156, Middle Region
14
10
4
2
1
Reactivity
Human
25
4
4
3
3
3
2
2
2
2
2
1
1
1
Host
Rabbit
25
Clonality
Polyclonal
Conjugate
This SRP72 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
24
17
14
7
5
5
1
1
Options
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Supplier Product No.
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Immunogen KLH conjugated synthetic peptide between 126~156 amino acids from the Center region of Human SRP72 Genename: SRP72
Isotype Ig
Specificity This antibody recognizes SRP72 (Center).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity Chromatography on Protein A
Alternative Name SRP72 (SRP72 Antibody Abstract)
Background Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.Synonyms: Signal recognition particle 72 kDa protein
Gene ID 6731
NCBI Accession NP_008878
UniProt O76094
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunofluorescence (IF) image for anti-Signal Recognition Particle 72kDa (SRP72) (AA 126-156), (Middle Region) antibody (ABIN453397) Immunofluorescence analysis of AP17766PU-N SRP72 antibody (Center) with Hela cells. 0...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Signal Recognition Particle 72kDa (SRP72) (AA 126-156), (Middle Region) antibody (ABIN453397) AP17766PU-N SRP72 antibody staining of Formalin-Fixed, Paraffin-Embedded Human pancre...
Western Blotting (WB) image for anti-Signal Recognition Particle 72kDa (SRP72) (AA 126-156), (Middle Region) antibody (ABIN453397) Western blot analysis of AP17766PU-N SRP72 antibody in Hela cell line lysates (35 µg/...
Background publications Utz, Hottelet, Le, Kim, Geiger, van Venrooij, Anderson: "The 72-kDa component of signal recognition particle is cleaved during apoptosis." in: The Journal of biological chemistry, Vol. 273, Issue 52, pp. 35362-70, 1999 (PubMed).

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