SRSF2 antibody (Middle Region)
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- Target See all SRSF2 Antibodies
- SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))
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Binding Specificity
- AA 83-113, Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SRSF2 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody reacts to SFRS2.
- Purification
- Saturated Ammonium Sulfate (SAS) precipitation
- Immunogen
- KLH conjugated synthetic peptide selected from aa 83-113 from the Center region of human SFRS2
- Top Product
- Discover our top product SRSF2 Primary Antibody
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- Application Notes
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))
- Alternative Name
- SFRS2 / SC-35 (SRSF2 Products)
- Synonyms
- PR264 antibody, SC-35 antibody, SC35 antibody, SFRS2 antibody, SFRS2A antibody, SRp30b antibody, D11Wsu175e antibody, MRF-1 antibody, Pr264 antibody, Sfrs10 antibody, Sfrs2 antibody, pr264 antibody, sc-35 antibody, sc35 antibody, sfrs2 antibody, sfrs2a antibody, srp30b antibody, serine and arginine rich splicing factor 2 antibody, serine/arginine-rich splicing factor 2 antibody, serine/arginine-rich splicing factor 2 L homeolog antibody, SRSF2 antibody, Srsf2 antibody, srsf2.L antibody
- Background
- SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3' and can bind to beta-globin mRNA and commit it to the splicing pathway.Synonyms: Nuclear Speckle Marker, PR264, Splicing component 35 kDa, Splicing factor SC35, Splicing factor arginine/serine-rich 2
- Gene ID
- 6427
- NCBI Accession
- NP_003007
- UniProt
- Q01130
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