ACVR1C/ALK7 antibody (AA 72-121)

Catalog No. ABIN6743671

Product Details anti-ACVR1C/ALK7 Antibody

Target: ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))

Binding Specificity: AA 72-121

Reactivity: Human, Rat, Cow, Rabbit, Guinea Pig, Horse, Bat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACVR1C/ALK7 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human ACVR1C

Predicted Reactivity: Percent identity by BLAST analysis: Bovine, Rabbit, Horse (100%) Mouse, Pig (92%) Rat (85%) Guinea pig (80%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa72-121 of human ACVR1C (Q8NER5, NP_660302). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Bovine, Bat, Rabbit, Horse (100%), Mouse, Pig (92%), Rat, Elephant (85%), Guinea pig (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for ACVR1C/ALK7

Target: ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))

Alternative Name: ACVR1C / ALK7 (ACVR1C Products)

Synonyms: ACVRLK7 antibody, ALK7 antibody, Alk-7 antibody, C230097P10 antibody, Alk7 antibody, habrec1 antibody, activin A receptor type 1C antibody, activin A receptor, type IC antibody, ACVR1C antibody, Acvr1c antibody

Background: Name/Gene ID: ACVR1C
Subfamily: Activin/TGFb
Family: Protein Kinase

Synonyms: ACVR1C, Activin receptor-like kinase 7, ACTR-IC, Activin receptor type IC, ACVRLK7, Activin receptor type-1C, ALK7, Activin A receptor, type IC, ALK-7

Gene ID: 130399

NCBI Accession: NP_660302

UniProt: Q8NER5

Pathways: Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity