STAT5B antibody (pSer731)

Catalog No. ABIN481856

The Rabbit Polyclonal anti-STAT5B antibody is suitable to detect STAT5B in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for STAT5B antibody (pSer731) (ABIN481856)

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT5B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-STAT5B Antibody

Binding Specificity: AA 697-746, pSer731

Specificity:

STAT5B (Phospho-Ser731) Antibody detects endogenous levels of STAT5B only when phosphorylated at Ser731.

PhosphorylationH:S731 M:S730 R:S730

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human STAT5B around the phosphorylation site of Ser731.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

Comment:

Unigene-Number: Hs.714309 (NCBI Gene Symbol: STAT5B)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for STAT5B

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Alternative Name: STAT5B

Background:

Synonyms: Signal transducer and activator of transcription 5B

NCBI Gene Symbol: STAT5B

Molecular Weight: 89 kDa

Gene ID: 6777

OMIM: 245590

UniProt: P51692

Pathways: JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation