Cyclin-Dependent Kinase 7 (CDK7) antibody

Antigen: Cyclin-Dependent Kinase 7 (CDK7)

Synonyms: CAK, p34, p37, CAK1, MO15, STK1, CDKN7, p39MO15, Crk4, Cdkn7, AI323415, AI528512, C230069N13, CDK7, DmCDK7, DmMO15, cdk-7, dCdk7, p40[MO15], DmelCG3319, CG3319, MGC85821, zgc:85821, MGC140417, cak1, stk1, cdkn7, p39mo15, p40MO15

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN487290

Additional Information

Alternative name: CDK7

Gene ID: CDK7

Immunogen: The immunogen for anti-CDK7 antibody: synthetic peptide directed towards the C terminal of human CDK7

Sequence: NRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALE QGGLPKKLIF

Cross-Reactivity: Human

Format: Lyophilized

Reconstitution: Add 100 µl of distilled water. Final anti-CDK7 antibody concentration is 1 mg/ml.

Description: Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcripti

Characteristics: Antigen Size: 346 amino acids

Molecular Weight: 39kDa

Synonyms: CAK, p34, p37, CAK1, MO15, STK1, CDKN7, p39MO15, Crk4, Cdkn7, AI323415, AI528512, C230069N13, CDK7, DmCDK7, DmMO15, cdk-7, dCdk7, p40[MO15], DmelCG3319, CG3319, MGC85821, zgc:85821, MGC140417, cak1, stk1, cdkn7, p39mo15, p40MO15

Application Details

Application Notes: WB Suggested Anti-CDK7 Antibody Titration: 1ug/ml
Positive Control: Jurkat cell lysate.

Purification: Protein A purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Research Area: Cell Cycle

Restrictions: For Research Use only

Images

WB Suggested Anti-CDK7 Antibody Titration: 1ug/ml
Positive Control: Jurkat cell lysate

Publications

Product: Tassan, Schultz, Bartek et al.: "Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)." in: The Journal of cell biology, Vol. 127, Issue 2, pp. 467-78, 1994 (PubMed).