CDK7 antibody (C-Term)

Catalog No. ABIN2792153

This Rabbit Polyclonal antibody specifically detects CDK7 in WB, IHC and IP. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Pig, Dog and Guinea Pig.

Quick Overview for CDK7 antibody (C-Term) (ABIN2792153)

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-CDK7 Antibody

Binding Specificity: C-Term

Purpose: CDK7 Antibody - C-terminal region

Sequence: NRPGPTPGCQ LPRPNCPVET LKEQSNPALA IKRKRTEALE QGGLPKKLIF

Predicted Reactivity: Cow: 100%, Dog: 94%, Guinea Pig: 94%, Horse: 100%, Human: 100%, Mouse: 88%, Pig: 100%, Rat: 88%

Characteristics: This is a rabbit polyclonal antibody against CDK7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDK7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDK7

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Alternative Name: CDK7

Background:

Background Information: Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcripti

Gene Name: Cyclin-dependent kinase 7

Alternative Symbols: CAK, CAK1, HCAK, MO15, STK1, CDKN7, p39MO15

Protein Name: Cyclin-dependent kinase 7

Molecular Weight: 39kDa

Gene ID: 1022

NCBI Accession: NP_001790

UniProt: P50613

Pathways: Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase