Cadherin 1 (CDH1) antibody

Antigen: Cadherin 1 (CDH1)

Synonyms: cdh1, E-cadherin, si:dz180o5.2, dZ71B9.1, si:dz180o5.1, CDH1, uvo, lcam, E-Cad, XBcad, l-cam, xcdh1, cdhc-A, xb-cad, XTCAD-1, c-cadherin, cadherin-1, uvomorulin, XB-cadherin, UVO, CDHE, ECAD, LCAM, Arc-1, CD324, HPT1, CDH16, HPT-1, FLJ26931, MGC138218, MGC142024, cad17, hpt1, cdh16, hpt-1, LI-cadherin, cadherin-17

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Catalog no.: ABIN498093

Additional Information

Characteristics: Synonyms: Epithelial cadherin, E-cadherin, Uvomorulin, CAM 120/80, CDH1, CDHE, UVO

Alternative name: CD324 / Cadherin-1

Gene ID: 999

Swiss-Prot: P12830

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Description: Cadherins are members of a multigene family of single chain glycoprotein receptorsmediating calcium dependent cell-cell adhesion. They play an important role in the growthand development of cells via the mechanisms of control of tissue architecture and themaintenance of tissue integrity. Cadherins are expressed in a tissue specific manner andand are required for assembly of cells into solid tissue. Individual cadherin molecules areknown to co-operate with each other to form a linear cell adhesion zipper. In adhesionjunctions cadherins are bound to beta and gamma catenins which in turn bind to alphacatenin, an actin binding protein. Cadherins play an important part in tumor invasion andmetastasis.

Specificity: This antibody antibody detects endogenous levels of E-Cadherin protein. Species: Human, Mouse and Rat. Others not tested.

Synonyms: cdh1, E-cadherin, si:dz180o5.2, dZ71B9.1, si:dz180o5.1, CDH1, uvo, lcam, E-Cad, XBcad, l-cam, xcdh1, cdhc-A, xb-cad, XTCAD-1, c-cadherin, cadherin-1, uvomorulin, XB-cadherin, UVO, CDHE, ECAD, LCAM, Arc-1, CD324, HPT1, CDH16, HPT-1, FLJ26931, MGC138218, MGC142024, cad17, hpt1, cdh16, hpt-1, LI-cadherin, cadherin-17

Application Details

Application Notes: Western Blots: 1/500~1/1000. Immunohistochemistry: 1/50~1/200. Immunofluorescence: 1/100~1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 1.0 mg/ml

Purification: Aff - Purified

Buffer: Phosphate buffered saline (PBS), pH~7.2 containing 15 mM Sodium Azideas preservative.

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Research Area: Extracellular Matrix, Signaling, Cytoskeleton

Restrictions: For Research Use only