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DEFa3 antibody
DEFa3
Reactivity: Human
IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DEFa3 Antibody
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Target
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DEFa3
(Defensin, alpha 3, Neutrophil-Specific (DEFa3))
Reactivity
All reactivities for DEFa3 antibodies
Human
Host
All hosts for DEFa3 antibodies
Rabbit
Clonality
All clonalities for DEFa3 antibodies
Polyclonal
Conjugate
All conjugates for DEFa3 antibodies
This DEFa3 antibody is un-conjugated
Application
All applications for DEFa3 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody detects endogenous levels of Defensin alpha-3 protein. (region surrounding Ser52)
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography
Purity
> 95 % by SDS-PAGE
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Application Details
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Application Notes
Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for DEFa3
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Target
DEFa3
(Defensin, alpha 3, Neutrophil-Specific (DEFa3))
Alternative Name
Defensin alpha 3 (DEFa3 Products )
Synonyms
Defa27 antibody, Defcr-3 antibody, Defcr3 antibody, DEF3 antibody, HNP-3 antibody, HNP3 antibody, HP-3 antibody, HP3 antibody, defensin, alpha 3, neutrophil-specific antibody, defensin, alpha, 3 antibody, defensin alpha 3 antibody, DEFA3 antibody, Defa3 antibody
Background
Defensins are a group of cyclic peptides containing 29-35 amino acids, which comprise approximately 30 % of the total protein content of neutrophil azurophilic granules. Various functions have been reported for the defensins, including antibacterial and antifungal activity and chemotactic activity for monocytes.Synonyms: DEF3, DEFA3, HNP-3, HP3, Neutrophil defensin 3
Gene ID
1668
NCBI Accession
NP_005208
UniProt
P59666
Pathways
Cellular Response to Molecule of Bacterial Origin
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