FANCL antibody (Internal Region)

Catalog No. ABIN499127

Product Details anti-FANCL Antibody

Target: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This FANCL antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-QNLKDVLEID FP

Specificity: This antibody is expected to recognize both isoforms (NP_001108108.1, NP_060532.2).

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to Human FANCL (NP_001108108.1 and NP_060532.2). Genename: FANCL

Application Details

Application Notes: Peptide ELISA: Limit Dilution: 1/16000. Western blot: 1-3 μg/mL. Detects a band of approx. 45 kDa in Human Bone Marrow lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FANCL

Target: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Alternative Name: FANCL (FANCL Products)

Synonyms: FAAP43 antibody, PHF9 antibody, POG antibody, 2010322C19Rik antibody, AW554273 antibody, B230118H11Rik antibody, Phf9 antibody, Pog antibody, gcd antibody, Fanconi anemia complementation group L antibody, Fanconi anemia, complementation group L antibody, FANCL antibody, Fancl antibody

Background: FANCL is a ubiquitin ligase protein that mediates ubiquitination of FANCD2, a key step in the DNA damage pathway.Synonyms: E3 ubiquitin-protein ligase FANCL, FAAP43, Fanconi anemia group L protein, Fanconi anemia-associated polypeptide of 43 kDa, PHF9

Molecular Weight: 43.4kDa (NP_001108108.1).

Gene ID: 55120

NCBI Accession: NP_001108108

UniProt: Q9NW38

Pathways: DNA Damage Repair