TLR6 antibody (N-Term)
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- Target See all TLR6 Antibodies
- TLR6 (Toll-Like Receptor 6 (TLR6))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TLR6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects CD286 / TLR6 at N-term.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse
- Purification
- Peptide affinity chromatography
- Immunogen
- TLR6 antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human TLR6.
- Isotype
- IgG
- Top Product
- Discover our top product TLR6 Primary Antibody
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- Application Notes
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ELISA. Western blot. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- TLR6 (Toll-Like Receptor 6 (TLR6))
- Alternative Name
- CD286 / TLR6 (TLR6 Products)
- Synonyms
- TLR1 antibody, TLR16 antibody, CD286 antibody, TLR-6 antibody, toll-like receptor 1 family member A antibody, toll like receptor 6 antibody, toll-like receptor 6 antibody, TLR1A antibody, TLR6 antibody, Tlr6 antibody
- Background
- Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69 % sequence identify (4). Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan (5). Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses (6).Synonyms: Toll-like receptor 6
- Gene ID
- 10333
- NCBI Accession
- NP_006059
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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