Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5) (Middle Region) antibody

Details for Product No. ABIN501747
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms zgc:63502, wu:fi46f11, TonEBP, NFAT5, nfatz, orebp, nf-at5, nfatl1, tonebp, DKFZp469P1514, AI225870, B130038B15Rik, CAG-8, CAG80, NFATL1, OREBP, mKIAA0827, NF-AT5, NFATZ, TONEBP, Nfat
Epitope
Middle Region
(17), (8), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(56), (44), (26), (24), (24), (12)
Host
Rabbit
(52), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(27), (22), (20), (9), (5), (5), (3), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN501747
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the middle region of human NFAT5
Sequence PGQPQNEGQP PVTTLLSQQM PENSPLASSI NTNQNIEKID LLVSLQNQGN
Predicted Reactivity Guinea pig : 100 %, Human : 100 %, Bovine : 90 %, Rabbit : 90 %, Dog : 80 %, Horse : 80 %, Pig : 80 %
Characteristics This is a rabbit polyclonal antibody against NFAT5. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name NFAT5
Background NFAT5 is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements.The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.
Molecular Weight 166 kDa
Gene ID 10725
NCBI Accession NP_006590, NM_006599
UniProt O94916
Research Area Chromatin and Nuclear Signaling, Transcription Factors, Adaptive Immunity
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1531 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5) (Middle Region) antibody WB Suggested Anti-NFAT5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysate
Background publications Zhou, Ferraris, Dmitrieva et al.: "MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: opposite roles of p38alpha and p38delta." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 14, pp. 5620-5, 2008 (PubMed).

Validation Images
Did you look for something else?
back to top