Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (N-Term) antibody

Details for Product No. ABIN502652
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms Tak1, B430101B05, C87327, TAK1, TR2R1, TR4, hTAK1, Tr4, mKIAA4145, gb:dq017625, im:6911408
Epitope
N-Term
(37), (25), (16), (12), (12), (12), (12), (9), (8), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human
(149), (117), (115), (74), (61), (48), (15), (2), (1), (1), (1), (1)
Host
Rabbit
(140), (15)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (8), (8), (6), (6), (6), (6), (6), (6), (6), (6), (2), (2), (2)
Application
Western Blotting (WB)
(101), (60), (53), (28), (18), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN502652
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the N terminal of human NR2C2
Sequence INKHHRNRCQ FCRLKKCLEM GMKMESVQSE RKPFDVQREK PSNCAASTEK
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Chicken : 90 %
Characteristics This is a rabbit polyclonal antibody against NR2C2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name NR2C2
Background Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).
Molecular Weight 67 kDa
Gene ID 7182
NCBI Accession NP_003289, NM_003298
UniProt P49116
Research Area Chromatin and Nuclear Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 615 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (N-Term) antibody WB Suggested Anti-NR2C2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysate
Background publications Bouwmeester, Bauch, Ruffner et al.: "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ..." in: Nature cell biology, Vol. 6, Issue 2, pp. 97-105, 2004 (PubMed).

Validation Images
Did you look for something else?
back to top