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ASAP3 antibody (AA 550-800)
ASAP3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ASAP3 Antibody
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Target
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ASAP3
(ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3))
Binding Specificity
All epitopes for ASAP3 antibodies
AA 550-800
Reactivity
All reactivities for ASAP3 antibodies
Human
Host
All hosts for ASAP3 antibodies
Rabbit
Clonality
All clonalities for ASAP3 antibodies
Polyclonal
Conjugate
All conjugates for ASAP3 antibodies
This ASAP3 antibody is un-conjugated
Application
All applications for ASAP3 antibodies
Western Blotting (WB)
Purification
Protein A Chromatography
Immunogen
A partial length recombinant ASAP3 protein (amino acids 550-800) was used as the immunogen for this antibody.
Isotype
IgG
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Application Details
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Application Notes
WB: 2-4 μg/mL This antibody detects ~43 kDa band. The size corresponds to Isoform 2 (Uniprot ID-Q8TDY4-2) of ASAP3, the right size is ~99 kDa.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for ASAP3
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Target
ASAP3
(ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3))
Alternative Name
ASAP3 (ASAP3 Products )
Synonyms
DDEFL1 antibody, ddefl1 antibody, zgc:113885 antibody, ACAP4 antibody, CENTB6 antibody, UPLC1 antibody, 9430088F20Rik antibody, Ddefl1 antibody, Gm140 antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 antibody, development and differentiation enhancing factor-like 1 antibody, ASAP3 antibody, asap3 antibody, DDEFL1 antibody, Asap3 antibody
Background
ASAP3 belongs to Arf-specific GTPase-activating proteins which regulate Arfs by stimulating their intrinsic GTP hydrolysis. This protein contains a catalytic core of a PH (Pleckstrin Homology) domain, a GAP motif, and two ANK (Ankyrin) repeats. ASAP3 also associates with focal adhesions and with cytoplasmic membranes at the circular dorsal ruffles, where the actin skeleton is remodeled. Depletion of ASAP3 by RNA interference suppresses cell migration in wound healing.
Molecular Weight
43 kDa (Isoform)
Gene ID
55616
UniProt
Q8TDY4
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