FKBP5 antibody (C-Term)
-
- Target See all FKBP5 Antibodies
- FKBP5 (FK506 Binding Protein 5 (FKBP5))
-
Binding Specificity
- C-Term
-
Reactivity
- Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig, Zebrafish (Danio rerio)
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This FKBP5 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- CYLKLREYTK AVECCDKALG LDSANEKGLY RRGEAQLLMN EFESAKGDFE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against FKBP5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human FKBP5
- Top Product
- Discover our top product FKBP5 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 457 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- FKBP5 (FK506 Binding Protein 5 (FKBP5))
- Alternative Name
- FKBP5 (FKBP5 Products)
- Synonyms
- FKBP5 antibody, FKBP-5 antibody, AIG6 antibody, FKBP51 antibody, FKBP54 antibody, P54 antibody, PPIase antibody, Ptg-10 antibody, D17Ertd592e antibody, Dit1 antibody, si:zc263a23.8 antibody, wu:fc31g11 antibody, wu:fl87b03 antibody, zgc:64082 antibody, FK506 binding protein 5 antibody, FKBP5 antibody, fkbp5 antibody, Fkbp5 antibody
- Background
-
FKBP5 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FKBP51, FKBP54, MGC111006, P54, PPIase, Ptg-10, AIG6
Protein Interaction Partner: LRRC40, CXorf57, EGLN1, AGO2, CACYBP, CHORDC1, AGO1, KIAA1279, NUDCD3, GLMN, CDC37, SUGT1, PTGES3, NUDC, AHSA1, DNAJB6, AURKB, IKBKG, IRS4, TUBA1A, TTC4, PYGL, PDCD2, CDK11A, HGH1, C14orf80, MCMBP, PNPLA2, ANKMY2, CDC37L1, MCM4, ILK, HSP90AB1, HSP90AA1, H
Protein Size: 457 - Molecular Weight
- 51 kDa
- Gene ID
- 2289
- NCBI Accession
- NM_004117, NP_004108
- UniProt
- Q13451
-