Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (Middle Region) antibody

Details for Product No. ABIN503865
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Antigen
Synonyms HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, pp90RSK3, 90kDa, D17Wsu134e, Rps6ka-rs1, Rsk3, p90rsk, pp90rsk
Epitope
Middle Region
(28), (16), (12), (8), (8), (7), (6), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Human
(75), (58), (40), (24), (24), (12)
Host
Rabbit
(70), (12)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2)
Application
Western Blotting (WB)
(47), (31), (30), (12), (12), (6), (3), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN503865
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human RPS6KA2
Sequence LSRQDVHLVK GAMAATYFAL NRTPQAPRLE PVLSSNLAQR RGMKRLTSTR
Predicted Reactivity Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, Bovine : 90 %, Rabbit : 80 %
Characteristics This is a rabbit polyclonal antibody against RPS6KA2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name RPS6KA2
Background RPS6KA2 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Molecular Weight 81 kDa
Gene ID 6196
NCBI Accession NM_021135, NP_066958
UniProt Q15349
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 733 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (Middle Region) antibody WB Suggested Anti-RPS6KA2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate
Background publications Wissing, Jänsch, Nimtz et al.: "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 3, pp. 537-47, 2007 (PubMed).

Validation Images
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