NFKBIA antibody (AA 32-291)

Catalog No. ABIN531958

Product Details anti-NFKBIA Antibody

Target: NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))

Binding Specificity: AA 32-291

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NFKBIA antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Mouse monoclonal antibody raised against partial recombinant NFKBIA .

Cross-Reactivity: Human, Mouse

Immunogen: Recombinant protein corresponding to amino acids 32-291 of human NFKBIA.

Clone: 6A920

Isotype: IgG1

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.05 % BSA, 0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-NFKBIA antibody (ABIN531958)

Nishioka, Ikezoe, Jing, Umezawa, Yokoyama et al.: "DHMEQ, a novel nuclear factor-kappaB inhibitor, induces selective depletion of alloreactive or phytohaemagglutinin-stimulated peripheral blood mononuclear cells, decreases production of T helper type ..." in: Immunology, Vol. 124, Issue 2, pp. 198-205, (2008) (PubMed).

Endo, Nishio, Enzler, Cottam, Fukuda, James, Karin, Kipps: "BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathway." in: Blood, Vol. 109, Issue 2, pp. 703-10, (2007) (PubMed).

Vilimas, Mascarenhas, Palomero, Mandal, Buonamici, Meng, Thompson, Spaulding, Macaroun, Alegre, Kee, Ferrando, Miele, Aifantis: "Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia." in: Nature medicine, Vol. 13, Issue 1, pp. 70-7, (2007) (PubMed).

Strozyk, Pöppelmann, Schwarz, Kulms: "Differential effects of NF-kappaB on apoptosis induced by DNA-damaging agents: the type of DNA damage determines the final outcome." in: Oncogene, Vol. 25, Issue 47, pp. 6239-51, (2006) (PubMed).

Ishiguro, Ando, Maeda, Hasegawa, Kadomatsu, Ohmiya, Niwa, Xavier, Goto: "Paeonol attenuates TNBS-induced colitis by inhibiting NF-kappaB and STAT1 transactivation." in: Toxicology and applied pharmacology, Vol. 217, Issue 1, pp. 35-42, (2006) (PubMed).

Santhi, Sebastian, Varghese, Prakash, Pillai: "NF-kappaB and COX-2 during oral tumorigenesis and in assessment of minimal residual disease in surgical margins." in: Experimental and molecular pathology, Vol. 81, Issue 2, pp. 123-30, (2006) (PubMed).

Target Details for NFKBIA

Target: NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))

Alternative Name: NFKBIA / IKBA (NFKBIA Products)

Synonyms: IKBA antibody, MAD-3 antibody, NFKBI antibody, AI462015 antibody, Nfkbi antibody, RL/IF-1 antibody, ECI-6/IKBA antibody, NFKBIA antibody, ikbaB antibody, wu:fb81f08 antibody, zgc:56666 antibody, zgc:77616 antibody, ikbaA antibody, wu:fj16a07 antibody, zgc:85769 antibody, NFKB inhibitor alpha antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a antibody, NFKBIA antibody, Nfkbia antibody, nfkbiab antibody, nfkbiaa antibody

Gene ID: 4792

Pathways: NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling